A novel integration of brain structural and functional connectivity for identifying traumatic brain injury induced perturbations

The ability of the brain to perform multiple complex tasks with fixed structures has yet to be fully elucidated. Structural connectivity (SC) and functional connectivity (FC) have been increasingly used to understand the structure and function of the brain respectively. However, a limited number of studies have explored the relationship between both entities especially in translational animal models. Our findings demonstrated that SC-FC integration model improved detection of significant differences in brain connectivity and pinpoints hub regions that had been directly impacted by TBI. You can read more about these findings by clicking the following link: https://pubmed.ncbi.nlm.nih.gov/40273994/.