| Genipin rescues developmental and degenerative defects in familial dysautonomia models and accelerates axon regeneration K Saito-Diaz, P Dietrich, T Saini, MM Rashid, HF Wu, M Ishan, X Sun, …Science Translational Medicine 16 (774), eadq2418 | 2024 |
| Novel cross-species salivary gland-parasympathetic neuron coculture system HF Wu, M Ishan, MM Rashid, HX Liu, N Zeltner. Bio-protocol 14 (21) | 2024 |
| The duct of von Ebner’s glands is a source of Sox10 + taste bud progenitors and susceptible to pathogen infections W Yu, ME Kastriti, M Ishan, SK Choudhary, MM Rashid, N Kramer, …Frontiers in Cell and Developmental Biology 12, 1460669 | 2024 |
| The main duct of von Ebner’s glands is a source of Sox10+ taste bud progenitors and susceptible to pathogen infections W Yu, ME Kastriti, M Ishan, SK Choudhary, N Kramer, MM Rashid, …bioRxiv, 2024.05. 14.594215 | 2024 |
| Parasympathetic neurons derived from human pluripotent stem cells model human diseases and development HF Wu, K Saito-Diaz, CW Huang, JL McAlpine, DE Seo, DS Magruder, …Cell Stem Cell 31 (5), 734-753. e8 | 2024 |
| Taste papilla cell differentiation requires the regulation of secretory protein production by ALK3-BMP signaling in the tongue mesenchyme M Ishan, Z Wang, P Zhao, Y Yao, SL Stice, L Wells, Y Mishina, HX Liu. Development 150 (18), dev201838 | 2023 |
| O-GlcNAcylation is crucial for sympathetic neuron development, maintenance, functionality and contributes to peripheral neuropathy HF Wu, CW Huang, J Art, HX Liu, GW Hart, N Zeltner. Frontiers in Neuroscience 17, 1137847 | 2023 |
| Taste papilla cell differentiation requires tongue mesenchyme via ALK3-BMP signaling to regulate the production of secretory proteins M Ishan, Z Wang, P Zhao, Y Yao, S Stice, L Wells, Y Mishina, HX Liu. bioRxiv, 2023.04. 03.535414 | 2023 |
| Mesenchymal ALK3-BMP signaling regulates epithelial cell differentiation through governing the production of previously unappreciated secretory proteins M Ishan, Z Wang, P Zhao, Y Yao, S Stice, L Wells, Y Mishina, HX Liu. CHEMICAL SENSES 48 | 2023 |
| Norepinephrine transporter defects lead to sympathetic hyperactivity in Familial Dysautonomia models HF Wu, W Yu, K Saito-Diaz, CW Huang, J Carey, F Lefcort, GW Hart, …Nature Communications 13 (1), 7032 | 2022 |
| Mesenchymal BMP-ALK3 signaling promotes taste papilla cell differentiation through suppressing the production of inhibitory secretory proteins M Ishan, Z Wang, Y Mishina, HX Liu. CHEMICAL SENSES 47 | 2022 |
| EVC2 regulates taste papilla development through tuning hedgehog signaling activities in a stage-and regionspecific manner Z Wang, H Zhang, M Ishan, Y Mishina, HX Liu. CHEMICAL SENSES 47 | 2022 |
| Deletion of Nf2 in neural crest‐derived tongue mesenchyme alters tongue shape and size, Hippo signalling and cell proliferation in a region‐and stage‐specific manner M Ishan, G Chen, W Yu, Z Wang, M Giovannini, X Cao, HX Liu. Cell Proliferation 54 (12), e13144 | 2021 |
| Norepinephrine transporter defects lead to sympathetic hyperactivity in stem cell and mouse models of Familial Dysautonomia HF Wu, W Yu, J Carey, F Lefcort, H Liu, N Zeltner | 2021 |
| ALK3-mediated BMP Signaling regulates Mesenchymal-Epithelial interactions to promote Taste Papilla Development through Secretory Factors. M Ishan, Z Wang, Y Mishina, HX Liu. CHEMICAL SENSES 46 | 2021 |
| A journey of searching taste bud progenitor cells under lingual epithelium W Yu, N Kramer, HX Liu. CHEMICAL SENSES 46 | 2021 |
| Evolvement of taste sensitivity and taste buds in chickens during selective breeding Y Yoshida, F Kawabata, S Tabata, SE Aggrey, R Rekaya, HX Liu. Poultry science 100 (6), 101113 | 2021 |
| Taste buds are not derived from neural crest in mouse, chicken, and zebrafish W Yu, Z Wang, B Marshall, Y Yoshida, R Patel, X Cui, R Ball, L Yin, …Developmental biology 471, 76-88 | 2021 |
| Disociación Celular Del Epitelio De La Lengua Y El Meténquima/Tejido Conectivo De Los Ratones Embrionarios-Día 12.5 Y 8-Semana-Viejo W Yu, M Ishan, Z Wang, HX Liu. Journal of Visualized Experiments (JoVE), e62163 | 2021 |
| Cell dissociation from the tongue epithelium and mesenchyme/connective tissue of embryonic-day 12.5 and 8-week-old mice W Yu, M Ishan, Z Wang, HX Liu. Journal of visualized experiments: JoVE, 10.3791/62163 | 2021 |
| EVC2 is an Essential Regulator for Taste Papilla and Taste bud Formation Z Wang, H Zhang, Y Mishina, HX Liu. CHEMICAL SENSES 46 | 2021 |
| SARS-CoV-2 Receptor ACE2 Is Enriched in a Subpopulation of Mouse Tongue Epithelial Cells in Nongustatory Papillae but Not in Taste Buds or Embryonic Oral … Z Wang, J Zhou, B Marshall, R Rekaya, K Ye, HX Liu. ACS pharmacology and translational science 3 (4), 749-758 | 2020 |
| SOX10–Cre-Labeled Cells Under the Tongue Epithelium Serve as Progenitors for Taste Bud Cells That Are Mainly Type III and Keratin 8-Low W Yu, M Ishan, Y Yao, SL Stice, HX Liu. Stem cells and development 29 (10), 638-647 | 2020 |
| Increased activity of mesenchymal ALK2‐BMP signaling causes posteriorly truncated microglossia and disorganization of lingual tissues M Ishan, G Chen, C Sun, SY Chen, Y Komatsu, Y Mishina, HX Liu. genesis 58 (1), e23337 | 2020 |
| Bitter Taste Receptor T2R7 and Umami Taste Receptor Subunit T1R1 are Expressed Largely in Vimentin-Negative Taste Bud Cells of Chickens Y Yoshida, Z Wang, KF Tehrani, EG Pendleton, R Tanaka, LJ Mortensen, …CHEMICAL SENSES 44 (7), E52-E53 | 2019 |
| Early taste buds are from Shh+ epithelial cells of tongue primordium in distinction from mature taste bud cells which arise from surrounding tissue compartments N Kramer, G Chen, M Ishan, X Cui, HX Liu. Biochemical and biophysical research communications 515 (1), 149-155 | 2019 |
| Bitter taste receptor T2R7 and umami taste receptor subunit T1R1 are expressed highly in Vimentin-negative taste bud cells in chickens Y Yoshida, Z Wang, KF Tehrani, EG Pendleton, R Tanaka, LJ Mortensen, …Biochemical and Biophysical Research Communications 511 (2), 280-286 | 2019 |
| Abundant proliferating cells within early chicken taste buds indicate a potentially “built-in” progenitor system for taste bud growth during maturation in hatchlings Z Wang, Y Yoshida, NE Kramer, F Kawabata, S Tabata, WK Kim, HX Liu. Histology and histopathology 34 (5), 503 | 2018 |
| Distinct Progenitor Cell Niches Are Required for Taste Bud Formation, Maturation and Maintenance G Chen, B Marshall, N Kramer, HX Liu. CHEMICAL SENSES 43 (7), E177-E178 | 2018 |
| SOX10-expressing Cells Are Progenitors of a Unique Population of Differentiated Taste Bud Cells W Yu, B Marshall, HX Liu. CHEMICAL SENSES 43 (7), E254-E255 | 2018 |
| Abundant proliferating cells within chicken taste buds indicate a potentially” built-in” progenitor system for homeostasis Z Wang, NE Kramer, X Cui, F Kawabata, S Tabata, WK Kim, HX Liu. CHEMICAL SENSES 43 (7), E234-E234 | 2018 |
| ALK3-Mediated BMP Signaling in the Tongue Mesenchyme is Essential for the Proper Development of Tongue and Taste Papillae M Ishan, G Chen, S Patel, Y Mishina, H Liu. CHEMICAL SENSES 43 (7), E178-E179 | 2018 |
| SOX10-Cre labeled cells are distributed in mature taste buds in mouse tongue and soft palate W Yu, G Chen, B Marshall, H Liu. CHEMICAL SENSES 43 (4), E60-E60 | 2018 |
| RNA-Seq analysis for taste sensory organs in chickens: An ideal system for multidisciplinary study X Cu, B Marshall, N Shi, S Chen, R Rekaya, H Liu. CHEMICAL SENSES 43 (4), E104-E105 | 2018 |
| 50X10-Cre labeled neural crest derived cells are absent in taste buds of zebrafish B Marshall, R Ball, J Lauderdale, R Kelsh, H Liu. CHEMICAL SENSES 43 (4), E86-E87 | 2018 |
| Mesenchyme-Specific Activation of BMP Receptor ALK2, but not ALK3, Results in Altered Tongue Formation and Cell Differentiation M Ishan, G Chen, S Patel, B Marshall, Y Mishina, HX Liu. CHEMICAL SENSES 43 (4), E42-E42 | 2018 |
| Neurofibromatosis 2 (NF2) in tongue mesenchyme is a key factor for the normal development of tongue and taste papillae G Chen, M Ishan, X Wang, W Yu, X Cao, M Giovannini, HX Liu. CHEMICAL SENSES 43 (4), E41-E41 | 2018 |
| An update on the sense of taste in chickens: A better developed system than previously appreciated HX Liu, P Rajapaksha, Z Wang, NE Kramer, BJ Marshall. Journal of nutrition and food sciences 8 (2), 686 | 2018 |
| Contribution of cranial neural crest cells to mouse skull development T Wu, G Chen, F Tian, HX Liu. International Journal of Developmental Biology 61 (8-9), 495-503 | 2017 |
| RNA-Seq analysis on chicken taste sensory organs: An ideal system to study organogenesis X Cui, B Marshall, N Shi, SY Chen, R Rekaya, HX Liu. Scientific Reports 7 (1), 9131 | 2017 |
| Specific and spatial labeling of P0‐Cre versus Wnt1‐Cre in cranial neural crest in early mouse embryos G Chen, M Ishan, J Yang, S Kishigami, T Fukuda, G Scott, MK Ray, C Sun, …genesis 55 (6), e23034 | 2017 |
| Pig induced pluripotent stem cell-derived neural rosettes parallel human differentiation into sensory neural subtypes RL Webb, A Gallegos-Cárdenas, CN Miller, NJ Solomotis, HX Liu, …Cellular Reprogramming 19 (2), 88-94 | 2017 |
| Labeling and analysis of chicken taste buds using molecular markers in oral epithelial sheets P Rajapaksha, Z Wang, N Venkatesan, KF Tehrani, J Payne, …Scientific reports 6 (1), 37247 | 2016 |
| Distribution of α-Gustducin and Vimentin in premature and mature taste buds in chickens N Venkatesan, P Rajapaksha, J Payne, F Goodfellow, Z Wang, …Biochemical and Biophysical Research Communications 479 (2), 305-311 | 2016 |
| Development of Multipolar Cell Shape in Mouse Corneal Endothelium DM Defoe, J Fleenor, K King, B Marshall, T Harrison, HX Liu. Investigative Ophthalmology and Visual Science 57 (12), 5295-5295 | 2016 |
| BMP Receptor Alk2 Mediates Mesenchymal-Epithelial Interactions for the Development of Mouse Tongue and Taste Papillae M Ishan, M Ishan, B Marshall, S Lalani, N Venketasan, P Rajapaksha, …CHEMICAL SENSES 41 (7), E43-E44 | 2016 |
| Podoplanin (PDPN) Plays Important Roles in the Development of Taste Organs in Mice N Venkatesan, M Toda, L Bonewald, Y Mishina, HX Liu. CHEMICAL SENSES 41 (7), E18-E18 | 2016 |
| K14-Cre and Dermo1-Cre Each Labels a Subpopulation of Taste Bud Cells in Mice G Chen, B Marshall, N Venkatesan, HX Liu. CHEMICAL SENSES 41 (7), E44-E44 | 2016 |
| Taste bud labeling in whole tongue epithelial sheet in adult mice N Venkatesan, K Boggs, HX Liu. Tissue Engineering Part C: Methods 22 (4), 332-337 | 2016 |
| Corneal endothelial cells possess an elaborate multipolar shape to maximize the basolateral to apical membrane area TA Harrison, Z He, K Boggs, G Thuret, HX Liu, DM Defoe. Molecular Vision 22, 31 | 2016 |
| Contribution of underlying connective tissue cells to taste buds in mouse tongue and soft palate K Boggs, N Venkatesan, I Mederacke, Y Komatsu, S Stice, RF Schwabe, …PloS one 11 (1), e0146475 | 2016 |
| Neural Crest Derived Cells are Distributed in Mature Taste Buds in Adult Mice K Boggs, N Venkatesan, SL Stice, Y Mishina, HX Liu. CHEMICAL SENSES 40 (7), 650-651 | 2015 |
| Multiple Shh signaling centers participate in fungiform papilla and taste bud formation and maintenance HX Liu, A Ermilov, M Grachtchouk, L Li, DL Gumucio, AA Dlugosz, …Developmental biology 382 (1), 82-97 | 2013 |
| Neural crest contribution to lingual mesenchyme, epithelium and developing taste papillae and taste buds HX Liu, Y Komatsu, Y Mishina, CM Mistretta. Developmental biology 368 (2), 294-303 | 2012 |
| Separate and distinctive roles for Wnt5a in tongue, lingual tissue and taste papilla development HX Liu, AS Grosse, K Iwatsuki, Y Mishina, DL Gumucio, CM Mistretta. Developmental biology 361 (1), 39-56 | 2012 |
| Neuronal and Neural Crest Cell Markers Identify Specific Cell Types in Developing Tongue and Taste Papillae HX Liu, Y Komatsu, Y Mishina, C Mistretta. CHEMICAL SENSES 34 (7), A104-A104 | 2009 |
| Wnt5a has Stage and Location Specific Effects in Embryonic Tongue Epithelium and Mesenchyme CM Mistretta, HX Liu, AMS Grosse, KD Walton, DL Gumucio. CHEMICAL SENSES 34 (7), A107-A108 | 2009 |
| WNT5a in tongue and fungiform papilla development: distinct roles compared with WNT10b and other morphogenetic proteins HX Liu, AMS Grosse, KD Walton, DA Saims, DL Gumucio, CM Mistretta. Annals of the New York Academy of Sciences 1170 (1), 11-17 | 2009 |
| Wnt5a in Tongue and Taste Papilla Development HX Liu, AMS Grosse, KD Walton, DA Saims, DL Gumucio, CM Mistretta. CHEMICAL SENSES 33 (8), S3-S3 | 2008 |
| Gene Array Analysis to Identify Cell Cycle Target Genes of Shh Signal Disruption in Fungiform Papilla Formation CM Mistretta, DA Saims, HX Liu, L Hu. CHEMICAL SENSES 33 (8), S73-S73 | 2008 |
| Fungiform papilla pattern: EGF regulates inter‐papilla lingual epithelium and decreases papilla number by means of PI3K/Akt, MEK/ERK, and p38 MAPK signaling HX Liu, BS Henson, Y Zhou, NJ D’Silva, CM Mistretta. Developmental dynamics: an official publication of the American Association … | 2008 |
| Wnt signaling interacts with Shh to regulate taste papilla development K Iwatsuki, HX Liu, A Grónder, MA Singer, TF Lane, R Grosschedl, …Proceedings of the National Academy of Sciences 104 (7), 2253-2258 | 2007 |
| Repeated 100 Hz TENS for the treatment of chronic inflammatory hyperalgesia and suppression of spinal release of substance P in monoarthritic rats HX Liu, JB Tian, F Luo, YH Jiang, ZG Deng, L Xiong, C Liu, JS Wang, …Evidence‐Based Complementary and Alternative Medicine 4 (1), 65-75 | 2007 |
| Bone morphogenetic proteins and noggin: inhibiting and inducing fungiform taste papilla development Y Zhou, HX Liu, CM Mistretta. Developmental biology 297 (1), 198-213 | 2006 |
| EGF and BMP inhibition of fungiform papilla formation in embryonic tongue HX Liu, YQ Zhou, BS Henson, NJ D’Silva, CM Mistretta. Developmental Biology 295 (1), 456 | 2006 |
| Development of fungiform papillae: patterned lingual gustatory organs CM Mistretta, HX Liu. Archives of histology and cytology 69 (4), 199-208 | 2006 |
| Galaninergic mechanisms at the spinal level: focus on histochemical phenotyping M Landry, HX Liu, TJ Shi, P Brumovsky, F Nagy, T Hökfelt. Neuropeptides 39 (3), 223-231 | 2005 |
| Development of gustatory organs and innervating sensory ganglia CM Mistretta, A Grigaliunas, HX Liu. Chemical Senses 30 (suppl_1), i52-i53 | 2005 |
| Sonic hedgehog exerts distinct, stage-specific effects on tongue and taste papilla development HX Liu, DK MacCallum, C Edwards, W Gaffield, CM Mistretta. Developmental biology 276 (2), 280-300 | 2004 |
| Effect of a graded single constriction of the rat sciatic nerve on pain behavior and expression of immunoreactive NPY and NPY Y1 receptor in DRG neurons and spinal cord PR Brumovsky, E Bergman, HX Liu, T Hökfelt, MJ Villar. Brain research 1006 (1), 87-99 | 2004 |
| Cyclopamine and jervine in embryonic rat tongue cultures demonstrate a role for Shh signaling in taste papilla development and patterning: fungiform papillae double in number … CM Mistretta, HX Liu, W Gaffield, DK MacCallum. Developmental biology 254 (1), 1-18 | 2003 |
| The participation of galanin in pain processing at the spinal level HX Liu, T Hökfelt. Trends in pharmacological sciences 23 (10), 468-474 | 2002 |
| Receptor subtype-specific pronociceptive and analgesic actions of galanin in the spinal cord: selective actions via GalR1 and GalR2 receptors HX Liu, P Brumovsky, R Schmidt, W Brown, K Payza, L Hodzic, C Pou, …Proceedings of the National Academy of Sciences 98 (17), 9960-9964 | 2001 |
| Effect of intrathecal galanin and its putative antagonist M35 on pain behavior in a neuropathic pain model HX Liu, T Hökfelt. Brain research 886 (1-2), 67-72 | 2000 |
| Decreased GDNF mRNA expression in dorsal spinal cord of unilateral arthritic rat M Fang, Y Wang, HX Liu, XS Liu, JS Han. Neuroreport 11 (4), 737-741 | 2000 |
| Nocistatin reverses the effect of orphanin FQ/nociceptin in antagonizing morphine analgesia CS Zhao, BS Li, GY Zhao, HX Liu, F Luo, Y Wang, JH Tian, JK Chang, …Neuroreport 10 (2), 297-299 | 1999 |
| Ho» kfelt T 2001) Receptor subtype-specific pronociceptive and analgesic actions of galanin in the spinal cord: Selective actions via GalR1 and GalR2 receptors HX Liu, P Brumovsky, R Schmidt, W Brown, K Payza, L Hodzic, C Pou, …Proc Natl Acad Sci USA 98, 9960-9964 | |