{"id":1019,"date":"2021-01-07T20:28:00","date_gmt":"2021-01-08T01:28:00","guid":{"rendered":"http:\/\/site.caes.uga.edu\/tnrrl\/?p=1019"},"modified":"2024-02-22T10:01:09","modified_gmt":"2024-02-22T15:01:09","slug":"alcohol-induced-brain-and-liver-damage-may-be-best-modeled-using-pigs","status":"publish","type":"post","link":"https:\/\/site.caes.uga.edu\/tnrrl\/2021\/01\/alcohol-induced-brain-and-liver-damage-may-be-best-modeled-using-pigs\/","title":{"rendered":"Alcohol induced brain and liver damage may be best modeled using pigs"},"content":{"rendered":"\n<p>Alcohol is one of the most commonly abused intoxicants with 1 in 6 adults at risk for alcohol use disorder (AUD). As such, rodent AUD models are widely studied however, inherent anatomical and physiological differences between rodents and humans pose a number of limitations in studying the complex nature of human AUD. Comparatively, this review describes how pigs and humans share anatomical similarities in the two major target organs of alcohol- the brain and liver. A porcine model of AUD possesses great translational potential that can significantly advance our current understanding of the complex development and continuance of AUD in humans. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33488396\/\" data-type=\"link\" data-id=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33551956\/\">Read more of this paper at <em>PubMed<\/em>\u00ae.\u00a0<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Alcohol is one of the most commonly abused intoxicants with 1 in 6 adults at risk for alcohol use disorder (AUD). As such, rodent AUD models are widely studied however, inherent anatomical and physiological differences between rodents and humans pose a number of limitations in studying the complex nature of human AUD. Comparatively, this review [&hellip;]<\/p>\n","protected":false},"author":722,"featured_media":1020,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1019","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publications"],"_links":{"self":[{"href":"https:\/\/site.caes.uga.edu\/tnrrl\/wp-json\/wp\/v2\/posts\/1019","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/site.caes.uga.edu\/tnrrl\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/site.caes.uga.edu\/tnrrl\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/site.caes.uga.edu\/tnrrl\/wp-json\/wp\/v2\/users\/722"}],"replies":[{"embeddable":true,"href":"https:\/\/site.caes.uga.edu\/tnrrl\/wp-json\/wp\/v2\/comments?post=1019"}],"version-history":[{"count":2,"href":"https:\/\/site.caes.uga.edu\/tnrrl\/wp-json\/wp\/v2\/posts\/1019\/revisions"}],"predecessor-version":[{"id":1204,"href":"https:\/\/site.caes.uga.edu\/tnrrl\/wp-json\/wp\/v2\/posts\/1019\/revisions\/1204"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/site.caes.uga.edu\/tnrrl\/wp-json\/wp\/v2\/media\/1020"}],"wp:attachment":[{"href":"https:\/\/site.caes.uga.edu\/tnrrl\/wp-json\/wp\/v2\/media?parent=1019"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/site.caes.uga.edu\/tnrrl\/wp-json\/wp\/v2\/categories?post=1019"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/site.caes.uga.edu\/tnrrl\/wp-json\/wp\/v2\/tags?post=1019"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}