{"id":151,"date":"2019-11-03T10:14:09","date_gmt":"2019-11-03T15:14:09","guid":{"rendered":"http:\/\/site.caes.uga.edu\/mitchumlab\/?page_id=151"},"modified":"2025-11-03T15:09:23","modified_gmt":"2025-11-03T20:09:23","slug":"primary-research-articles","status":"publish","type":"page","link":"https:\/\/site.caes.uga.edu\/mitchumlab\/primary-research-articles\/","title":{"rendered":"Research Articles"},"content":{"rendered":"\n

Members of the Mitchum lab are in bold<\/strong> (with the following designations: \u0166<\/sup>emeritus, \u00a7<\/sup><\/strong>post-doctoral researcher, \u00a3<\/sup><\/strong>graduate student, \u2260<\/sup>co-mentored graduate student, \u00b6<\/sup><\/strong>undergraduate student, \u2021<\/sup>research specialist). <\/p>\n\n\n\n

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  1. \u00a3<\/sup><\/strong>Basnet P<\/strong>, Pennewitt M, Meinhardt C, Dhital B, Cary T, Diers B, Mitchum MG<\/strong>, Tylka GL, Scaboo A. Strategic rotation of resistance genes to manage soybean cyst nematode population density and virulence. Plant Disease<\/em> 2025 (under review)<\/li>\n\n\n\n
  2. \u00a3<\/sup><\/strong>Gamage VA<\/strong>, \u00b6<\/sup>Strickland LW<\/strong>, Mitchum MG<\/strong>. A Rhizobium rhizogenes<\/em>-mediated transformation method coupling CRISPR\/Cas9-gene editing in soybean with high-throughput soybean cyst nematode greenhouse assays. BMC Methods<\/em> 2025 (accepted)<\/li>\n\n\n\n
  3. Vieira CC, Ferrari do Nascimento E, Acuna A, Usovsky M, \u2021<\/sup>Pominville A, Faske T, Li Z, Mitchum MG<\/strong>, Nguyen H, Shannon JG. Soybean resistance to southern root-knot nematode reduces nematode population density under field conditions. Crop Science<\/em> 2025 (accepted)<\/li>\n\n\n\n
  4. \u00a3<\/sup><\/strong>Goode K<\/strong>, Nienow T, Parrot W, Li Z, Mitchum MG<\/strong>. Candidate genes at the Rmi1<\/em> locus for resistance to Meloidogyne incognita<\/em> in soybean. Theoretical and Applied Genetics<\/em> 2025 (accepted) Theor Appl Genet<\/em>. 2025:138(11):286. doi: 10.1007\/s00122-025-05065-w<\/a><\/li>\n\n\n\n
  5. \u00a3<\/sup><\/strong>Goode K<\/strong>, Mitchum MG<\/strong>. Comparative transcriptomic analysis of soybean recombinant inbred lines differing at the Rmi1<\/em> locus for resistance to Meloidogyne incognita<\/em> during early stages of nematode infection. Phytopathology<\/em> 2025. https:\/\/doi.org\/10.1094\/PHYTO-04-25-0143-SC<\/a><\/li>\n\n\n\n
  6. \u00a7<\/sup><\/strong>Liu XL, Mitchum MG<\/strong>. Transcriptome and cell type signature analysis of laser-microdissected syncytia induced by the cyst nematode Heterodera schachtii<\/em> in Arabidopsis roots. <\/em>Molecular Plant-Nematode Interactions<\/em> 2025:38(4):529-542.  https:\/\/doi.org\/10.1094\/MPMI-03-25-0024-R<\/a><\/li>\n\n\n\n
  7. \u00a7<\/sup><\/strong>Liu XL, Mitchum MG<\/strong>. A major role of class III HD-ZIPs in promoting sugar beet cyst nematode syncytium formation in Arabidopsis<\/em>. PLoS Pathogens<\/em> 2024: 20(11) e1012610. https:\/\/doi.org\/10.1371\/journal.ppat.1012610<\/a><\/li>\n\n\n\n
  8. Samarakoon V, Owuocha LF, Hammond J, Mitchum MG<\/strong>, Beamer LJ. Key structural role of a conserved cis-proline revealed by the P285S variant of soybean serine hydroxymethyltransferase 8. Biochemical Journal<\/em> 2024: 481(21):1557-1568. https:\/\/doi.org\/10.1042\/BCJ20240338<\/a> <\/li>\n\n\n\n
  9. Owuocha LF, Mitchum MG<\/strong>, Beamer LJ. Structural insights into binding of polyglutamylated tetrahydrofolate by serine hydroxymethyltransferase 8 from soybean. Frontiers in Plant Science<\/em> 2024: 15:1451839. https:\/\/doi.org\/10.3389\/fpls.2024.1451839<\/a>  <\/li>\n\n\n\n
  10. \u00a3<\/sup><\/strong>Kwon KK<\/strong>, Viana JPG, Walden KO, Usovsky M, Scaboo AM, Hudson ME, Mitchum MG<\/strong>. Genome scans for selection signatures identify candidate virulence genes for adaptation of the soybean cyst nematode to host resistance. Molecular Ecology<\/em> 2024: 33(17) e17490. https:\/\/doi.org\/10.1111\/mec.17490<\/a><\/li>\n\n\n\n
  11. \u00a7<\/sup><\/strong>Liu XL, Mitchum MG<\/strong>. Evaluation of chemical-inducible gene expression systems for beet cyst nematode infection assays in Arabidopsis thaliana<\/em>. Molecular Plant-Nematode Interactions<\/em> 2024: 37(8):611-618. https:\/\/doi.org\/10.1094\/MPMI-04-24-0042-TA<\/a><\/li>\n\n\n\n
  12. \u00a3<\/sup><\/strong>Kwon KK<\/strong>, Masonbrink RE, Maier TR, \u00a3<\/sup>Gardner MN<\/strong>, Severin AJ, Baum TJ, Mitchum MG<\/strong>. Comparative transcriptomic analysis of soybean cyst nematode inbred populations non-adapted or adapted on soybean rhg1-\/Rhg4<\/em>-mediated resistance. Phytopathology<\/em> 2024: 114:2341-2350. https:\/\/doi.org\/10.1094\/PHYTO-03-24-0095-R<\/a><\/li>\n\n\n\n
  13. \u2260<\/sup><\/strong>Tran DT<\/strong>, Mitchum MG<\/strong>, Zhang S, Wallace JG, Li Z. Soybean microbiome composition and the impact of host plant resistance. Frontiers in Plant Science<\/em>, section Plant-Pathogen Interactions<\/em> 2024; 14:1326882, https:\/\/doi.org\/10.3389\/fpls.2023.1326882 <\/a> <\/li>\n\n\n\n
  14. *<\/sup>Usovsky M, *\u00a3<\/sup>Gamage VA<\/strong>, Meinhardt CG, Dietz N, Triller M, Basnet P, Gillman JD, Bilyeu KD, Song Q, Dhital B, Nguyen A, \u2020<\/sup>Mitchum MG<\/strong>, \u2020<\/sup>Scaboo A. Loss-of-function of an \u03b1-SNAP<\/em> gene confers resistance to soybean cyst nematode. Nat Comm, collection Molecular Basis of Plant-Pathogen Interactions <\/em>2023: 14(1):7629. *<\/sup>co-first authors; \u2020<\/sup>co-corresponding authors https:\/\/doi.org\/10.1038\/s41467-023-43295-y<\/a><\/li>\n\n\n\n
  15. Mahmood A, Bilyeu K, Skrabisova M, Biov\u00e1 J, De Meyer EJ, \u2021<\/sup>Meinhardt CG<\/strong>, Usovsky M, Song Q, Lorenz A, Mitchum MG<\/strong>, Shannon G, Scaboo A. Cataloging SCN resistance loci in North American public soybean breeding programs. Frontiers in Plant Science, section Plant- Pathogen Interactions <\/em>2023; 14:1270546, doi: 10.3389\/fpls.2023.1270546<\/a><\/li>\n\n\n\n
  16. Korasick DA, Owuocha LF, \u00a7<\/sup>Kandoth PK<\/strong>, Tanner JJ, Mitchum MG<\/strong>, Beamer LJ. Structural and functional analysis of two SHMT8 variants associated with soybean cyst nematode resistance. The<\/em> FEBS Journal<\/em> 2024; 291:323-337; http:\/\/doi.org\/10.1111\/febs.16971<\/a><\/li>\n\n\n\n
  17. \u00a3<\/sup><\/strong>Basnet P<\/strong>, Meinhardt CG, Dhital B, Nguyen A, Gillman JD, Joshi T, Mitchum MG<\/strong>, Scaboo, AM. Development of a standardized soybean cyst nematode screening assay in Pennycress and identification of resistant germplasm. Plant Disease<\/em>, 2024; 108:359-364, https:\/\/doi.org\/10.1094\/PDIS-05-23-0858-RE<\/a><\/li>\n\n\n\n
  18. \u00a7<\/sup>Rocha RO, \u0166<\/sup>Hussey RS, <\/strong>Pepi LE, Azadi P, Mitchum MG<\/strong>. Discovery of novel effector proteins produced in the dorsal gland of root-knot nematode adult females. Mol Plant-Microbe Interact<\/em>. 2023; 36(6):372-380 DOI: 10.1094\/MPMI-11-22-0232-R <\/a><\/li>\n\n\n\n
  19. Mitchum MG<\/strong>, \u2021<\/sup>Averitt B<\/strong>, \u00a3<\/sup>Goode K<\/strong>, Martin K, \u2021<\/sup>Lance K<\/strong>, \u00a3<\/sup>Mitchell M<\/strong>, \u0166<\/sup>Hussey RS<\/strong>, Jagdale G, Kemerait RC. Frequency of occurrence of Heterodera glycines<\/em> types, Meloidogyne<\/em> spp., and eight other nematode taxa associated with soybeans in Georgia.Plant Health Prog.<\/em> 2022; https:\/\/doi.org\/10.1094\/PHP-09-22-0096-S<\/a><\/strong><\/li>\n\n\n\n
  20. Mitchum MG<\/strong>, \u00a7<\/sup>Rocha RO<\/strong>, Huang G, Maier TR, Baum TJ, \u0166<\/sup>Hussey RS<\/strong>. Genome-guided reanalysis of root-knot nematode Meloidogyne incognita<\/em> esophageal gland cell-enriched sequence tag libraries: A resource for the discovery of novel effectors. PhytoFrontiers<\/em> 2022; https:\/\/doi.org\/10.1094\/PHYTOFR-09-22-0099-A<\/a><\/strong><\/li>\n\n\n\n
  21. Chen S, Mitchum MG<\/strong>, Wang X. Characterization and response of two potato receptor-like kinases to cyst nematode infection. 2022, Plant Signal. Behav.<\/em> 2022: 17(1):2148372. DOI: 10.1080\/15592324.2022.2148372 <\/a><\/li>\n\n\n\n
  22. \u2021<\/sup><\/strong>Verma A<\/strong>, \u00a3<\/sup>Lin M<\/strong>, \u00b6<\/sup>Smith D<\/strong>, \u00a7<\/sup>Lee C<\/strong>, Walker JC, Hewezi T, Davis EL, \u0166<\/sup>Hussey RS<\/strong>, Baum TJ, Mitchum MG<\/strong>. A novel sugar beet cyst nematode effector 2D01 targets the Arabidopsis HAESA receptor-like kinase. Mol. Plant Pathol<\/em>. 2022; 23(12):1765-1782. *See also the Molecular Plant Pathology Highlight<\/strong> (https:\/\/www.bspp.org.uk\/microscopic-roundworm-targets-key-protein-in-plant-cell-wall-for-feeding-site-formation-molecular-plant-pathology-highlight\/<\/a>) and Cover Image<\/strong> (https:\/\/bsppjournals.onlinelibrary.wiley.com\/toc\/13643703\/2022\/23\/12<\/a>)<\/li>\n\n\n\n
  23. \u00a3<\/sup><\/strong>Basnet P<\/strong>, \u2021<\/sup>Meinhardt CG<\/strong>, Usovsky M, Gillman JD, Joshi T, Song Q, Diers B, Mitchum MG<\/strong>, Scaboo A. Epistatic interaction between Rhg1-a<\/em> and Rhg2<\/em> in PI 90763 confers resistance to virulent soybean cyst nematode populations. Theoretical and Applied Genetics<\/em> 2022; 135 (6):2025-2039. DOI: 10.1007\/s00122-022-04091-2<\/a><\/li>\n\n\n\n
  24. Maier TR, Masonbrink RE, Paramasivan V, \u00a3<\/sup>Gardner M<\/strong>, \u2021<\/sup>Howland A<\/strong>, Mitchum MG<\/strong>, Baum TJ. Esophageal gland RNA-seq resource of a virulent and avirulent population of the soybean cyst nematode, Heterodera glycines<\/em>. Mol. Plant-Microbe Interact<\/em>. 2021;34(9):1084-1087. DOI: 10.1094\/MPMI-03-21-0051-A<\/a><\/li>\n\n\n\n
  25. \u2021<\/sup>Meinhardt C,<\/strong> \u2021<\/sup>Howland A<\/strong>, Ellersick M, Scaboo A, Diers B, Mitchum MG<\/strong>. Resistance gene pyramiding and rotation to combat widespread soybean cyst nematode virulence. Plant Disease<\/em> 2021; https:\/\/doi.org\/10.1094\/PDIS-12-20-2556-RE<\/a><\/li>\n\n\n\n
  26. Vieira CC, Chen P, Usovski M, Vuong T, \u2021<\/sup>Howland AD<\/strong>, Nguyen H, Li Z, Mitchum MG<\/strong>, Shannon G. Major QTL for resistance to southern root-knot nematode sustains soybean yield under nematode pressure. Crop Science<\/em> 2021; https:\/\/doi.org\/10.1002\/csc2.20443<\/a><\/li>\n\n\n\n
  27. Wang J<\/strong>, Dhroso A, \u00a7<\/sup>Liu X<\/strong>, Baum TJ, Hussey RS, Davis EL, Wang X, Korkin D, Mitchum MG<\/strong>. Phytonematode peptide effectors exploit a host post-translational trafficking mechanism to the ER secretory pathway using a novel translocation signal. New Phytologist<\/em> 2021; 229(1): 563-574. https:\/\/doi.org\/10.1111\/nph.16765<\/a> **See also the Commentary on this article by Frei dit Frey & Favery 229: 11\u201313<\/strong><\/a>.<\/li>\n\n\n\n
  28. *<\/sup><\/strong>Pogorelko G, *<\/sup>Wang J<\/strong>, Juvale PS, Mitchum MG<\/strong>, Baum TJ. Screening soybean cyst nematode effectors for their ability to suppress plant immunity. Molecular Plant Pathology <\/em>2020;21(9):1240-1247. *Equal contribution https:\/\/doi.org\/10.1111\/mpp.12972<\/a><\/li>\n\n\n\n
  29. *<\/sup><\/strong>Wang J<\/strong>, \u00a3*<\/sup>Yeckel G<\/strong>, \u00a7<\/sup>Kandoth PK<\/strong>, \u2021<\/sup>Wasala L<\/strong>, Hussey RS, Davis EL, Baum TJ, Mitchum MG<\/strong>. Targeted suppression of soybean BAG6 induced cell death by soybean cyst nematode effectors. Molecular Plant Pathology<\/em> 2020; 21(9):1227-1239 *Equal contribution https:\/\/doi.org\/10.1111\/mpp.12970<\/a><\/li>\n\n\n\n
  30. Korasick D<\/strong>, \u00a7<\/sup>Kandoth PK<\/strong>, Tanner J, Mitchum MG<\/strong>, Beamer L. Impaired folate binding of soybean SHMT8 underlies resistance to the soybean cyst nematode. Journal of Biological Chemistry<\/em> 2020;295(11):3708-3718. https:\/\/doi.org\/10.1074\/jbc.RA119.012256<\/a><\/li>\n\n\n\n
  31. Masonbrink R, Maier TR, Muppirala U, Seetharam AS, Lord E, Juvale PS, Schmutz J, Johnson NT, Korkin D, Mitchum MG<\/strong>, <\/strong>Mimee B, Eves-vn den Akker S, Hudson M, Severin AJ, Baum TJ. The genome of the soybean cyst nematode (Heterodera glycines<\/em>) reveals complex patterns of duplications involved in the evolution of parasitism genes. BMC Genomics <\/em>2019; 20:119. https:\/\/doi.org\/10.1186\/s12864-019-5485-8<\/a><\/li>\n\n\n\n
  32. \u2021<\/sup>Howland A<\/strong>, Monnig N, Mathesius J, Nathan M, Mitchum MG<\/strong>. Survey of Heterodera glycines<\/em> population levels and virulence phenotypes during 2015-2016 in Missouri. Plant Disease<\/em> 2018;102:2407-2410. https:\/\/doi.org\/10.1094\/PDIS-04-18-0650-SR<\/a><\/li>\n\n\n\n
  33. Barnes SN, Wram CL, Mitchum MG<\/strong>, Baum TJ. The plant-parasitic cyst nematode effector GLAND4 is a DNA-binding protein. Molecular Plant Pathology <\/em>2018; 19:2263-2276. https:\/\/doi.org\/10.1111\/mpp.12697<\/a><\/li>\n\n\n\n
  34. \u00a7<\/sup>Verma A<\/strong>, \u00a7<\/sup>Lee C<\/strong>, \u00b6<\/sup>Morriss S<\/strong>, \u00b6<\/sup>Odu F<\/strong>, \u00a7<\/sup>Kenning C<\/strong>, Rizzo N, Spollen WG, \u00a3<\/sup>Lin M<\/strong>, \u00b6<\/sup>McRae A<\/strong>, Givan SA, Hewezi T, Hussey R, Davis EL, Baum TJ, Mitchum MG<\/strong>. The novel cyst nematode effector protein 30D08 targets host nuclear functions to alter gene expression in feeding sites. New Phytologist<\/em> 2018; 219:697-713. https:\/\/doi.org\/10.1111\/nph.15179<\/a><\/li>\n\n\n\n
  35. Ruark CL, \u00a3<\/sup>Gardner M<\/strong>, Mitchum MG<\/strong>, Davis EL, Sit TL. Novel RNA viruses within plant parasitic nematodes. PLOS One<\/em> 2018; 13:e0193881. https:\/\/doi.org\/10.1371\/journal.pone.0193881<\/a><\/li>\n\n\n\n
  36. \u00a3<\/sup>Gardner M<\/strong>, Dhroso A, Johnson N, Davis EL, Baum TJ, Korkin D, Mitchum, MG<\/strong>. Novel global effector mining from the transcriptome of early life stages of the soybean cyst nematode Heterodera glycines<\/em>. Scientific Reports<\/em> 2018; 8:2505. https:\/\/doi.org\/10.1038\/s41598-018-20536-5<\/a><\/li>\n\n\n\n
  37. Kandoth PK<\/strong>, Liu S, \u00b6<\/sup>Prenger E<\/strong>, \u00b6<\/sup>Ludwig A<\/strong>, Lakhssassi N, \u2021<\/sup>Heinz R<\/strong>, Zhou Z, \u2021<\/sup>Howland A<\/strong>, Gunther J, Warren S, Dhroso A, LaFayette P, Tucker D, Johnson S, Anderson J, Alaswad A, Cianzio SR, Parrott WA, Korkin D, Meksem K, Mitchum MG<\/strong>. Systematic mutagenesis of serine hydroxymethyltransferase reveals an essential role in nematode resistance. Plant Physiology<\/em> 2017; 175:1370-1380. https:\/\/doi.org\/10.1104\/pp.17.00553<\/a><\/li>\n\n\n\n
  38. \u00a3<\/sup><\/strong>Dowd CD<\/strong>, Chronis D<\/strong>, Radakovic ZS, Siddique S, Schmulling T, Werner T, Kakimoto T, Grundler FMW, Mitchum MG<\/strong>. Divergent expression of cytokinin biosynthesis, signaling and catabolism genes underlying differences in feeding sites induced by cyst and root-knot nematodes. The Plant Journal<\/em> 2017; 92:211-228. https:\/\/doi.org\/10.1111\/tpj.13647<\/a><\/li>\n\n\n\n
  39. Liu S, Kandoth P<\/strong>, Lakhssassi N, \u00a3<\/sup>Kang J<\/strong>, Colantonio VN, \u2021<\/sup>Heinz R<\/strong>, \u00a3<\/sup>Yeckel G<\/strong>, Zhou Z, Bekal S, Dapprich J, Rotter B, Cianzio S, Mitchum MG<\/strong>, Meksem K. The soybean GmSNAP18 underlies two types of resistance to soybean cyst nematode. Nature Communications<\/em> 2017: 8:14822 https:\/\/doi.org\/10.1038\/ncomms14822<\/a><\/li>\n\n\n\n
  40. Ruark CL, Koenning SR, Davis EL, Opperman CH, Lommel SA, Mitchum MG<\/strong>, and Sit TL. Soybean cyst nematode culture collections and field populations from North Carolina and Missouri reveal high incidences of infection by viruses. PLOS One<\/em> 2017: 12(1): https:\/\/doi.org\/10.1371\/journal.pone.0171514<\/a><\/li>\n\n\n\n
  41. Guo X<\/strong>, \u00a7<\/sup>Wang J<\/strong>, \u00a3<\/sup>Gardner M<\/strong>, Fukuda H, Kondo Y, Etchells P, Wang X, and Mitchum MG<\/strong>. Identification of cyst nematode B-type CLE peptides and modulation of the vascular stem cell pathway for feeding cell formation. PLOS Pathogens<\/em> 2017: 13(2):e1006142. https:\/\/doi.org\/10.1371\/journal.pone.0171514<\/a><\/li>\n\n\n\n
  42. \u00a3<\/sup><\/strong>Gardner MN<\/strong>, \u2021<\/sup>Heinz R<\/strong>, Wang J<\/strong>, and Mitchum MG<\/strong>. Genetics and adaptation of soybean cyst nematode to broad spectrum soybean resistance. G3: Genes, Genomes, Genetics<\/em> 2017; 7(3) 835-841; https:\/\/doi.org\/10.1534\/g3.116.035964<\/a><\/li>\n\n\n\n
  43. Noon J, Mingsheng Q, Sill D, Muppirala U, Eves-van den Akker S, Maier T, Dobbs D, Mitchum MG<\/strong>, Hewezi T, Baum TJ. A Plasmodium-like virulence effector of the soybean cyst nematode suppresses plant innate immunity. New Phytologist<\/em> 2016; 212:444-460. https:\/\/doi.org\/10.1111\/nph.14047<\/a><\/li>\n\n\n\n
  44. Siddique S, Radakovic ZS, \u00a3<\/sup>De La Torre CM<\/strong>, Chronis D<\/strong>, Holbein J, Novak O, Matera C, Hutten M, Gutbrod P, Anjam MS, Rozanska E, Habbash S, Elashry AN, Sobczak M, Strnad M, Kakimoto T, Schmulling T, Mitchum MG<\/strong>, Grundler F. A plant-parasitic nematode releases cytokinins that control cell division and orchestrate feeding-site formation in host plants. Proceedings of the National Academy of Sciences<\/em> 2015;112(41):12669-74 https:\/\/doi.org\/10.1073\/pnas.1503657112<\/a><\/li>\n\n\n\n
  45. Pogorelko G, Juvale PS, Rutter WB, Hewezi T, Hussey R, Davis EL, Mitchum MG<\/strong>, Baum TJ. A cyst nematode effector binds to diverse plant proteins, increases nematode susceptibility and affects root morphology. Molecular Plant Pathology<\/em> 2015;17(6):832-44. https:\/\/doi.org\/10.1111\/mpp.12330<\/a><\/li>\n\n\n\n
  46. Nguyen, PDT, Pike S, Wang J<\/strong>, Poudel AN, \u2021<\/sup>Heinz R<\/strong>, Schultz JC, Koo AJ, Mitchum MG<\/strong>, Appel H, Gassmann W. The Arabidopsis immune regulator SRFR1 <\/em>dampens defences against herbivory by Spodoptera exigua<\/em> and parasitism by Heterodera schachtii<\/em>. Molecular Plant Pathology <\/em>2015;17(4):588-600. https:\/\/doi.org\/10.1111\/mpp.12304<\/a><\/li>\n\n\n\n
  47. Noon JB, Hewezi T, Maier TR, Simmons C, Wei J-Z, Wu G, Llaca V, Deschamps S, Davis EL, Mitchum MG<\/strong>, Hussey RS, Baum TJ. Eighteen new candidate effectors of the phytonematode Heterodera glycines produced specifically in the secretory esophageal gland cells during parasitism. Phytopathology<\/em> 2015;105(10):1362-72. https:\/\/doi.org\/10.1094\/PHYTO-02-15-0049-R<\/a><\/li>\n\n\n\n
  48. Hewezi T, Juvale P, Piya S, Maier TR, Rambani A, Hollis Rice J, Mitchum MG<\/strong>, Davis EL, Hussey RS, Baum TJ. The novel cyst nematode effector protein 10A07 targets and recruits host post-translational machinery to mediate its nuclear trafficking and promote parasitism. The Plant Cell<\/em> 2015;27(3):891-907 https:\/\/doi.org\/10.1105\/tpc.114.135327<\/a><\/li>\n\n\n\n
  49. Guo X<\/strong>, \u00a7<\/sup>Chronis D<\/strong>, \u00a3<\/sup>De La Torre Cuba CM<\/strong>, \u00b6<\/sup>Smeda J<\/strong>, Wang X, Mitchum MG<\/strong>. Enhanced resistance to soybean cyst nematode Heterodera glycines<\/em> in transgenic soybean by silencing putative CLE receptors. Plant Biotechnology Journal<\/em> 2015;13(6):801-10. https:\/\/doi.org\/10.1111\/pbi.12313<\/a><\/li>\n\n\n\n
  50. Chen S, Lang P, Chronis D, Zhang S, De Jong WS, Mitchum MG<\/strong>, Wang X. In planta processing and glycosylation of a nematode CLE effector and its interaction with a host CLV2-like receptor to promote parasitism. Plant Physiology<\/em> 2015 167;262-272. https:\/\/doi.org\/10.1104\/pp.114.251637<\/a><\/li>\n\n\n\n
  51. Rutter WB, Hewezi T, Maier TR, Mitchum MG<\/strong>, Davis EL, Hussey R, Baum TJ. Members of the Meloidogyne<\/em> avirulence protein family contain multiple ligand-like motifs. Phytopathology<\/em> 2014;104(8): 879-885. https:\/\/doi.org\/10.1094\/PHYTO-11-13-0326-R<\/a><\/li>\n\n\n\n
  52. Kandoth P<\/strong>, \u2021<\/sup>Heinz R<\/strong>, \u00a3<\/sup>Yeckel G<\/strong>, \u00a3<\/sup>Gross NW<\/strong>, Juvale PS, Hill J, Whitham SA, Baum TJ, Mitchum MG<\/strong>. A virus-induced gene silencing method to study soybean cyst nematode parasitism in Glycine max<\/em>. BioMed Central Research Notes<\/em> 2013;6:255. https:\/\/dx.doi.org\/10.1186%2F1756-0500-6-255<\/a><\/li>\n\n\n\n
  53. Replogle A<\/strong>, Wang J<\/strong>, \u00b6<\/sup>Paolillo V<\/strong>, \u00b6<\/sup>Smeda J<\/strong>, Kinoshita A, Durbak A, Tax FE, Wang X, Sawa S, and Mitchum MG<\/strong>. Synergistic interaction of CLAVATA1, CLAVATA2, and RECEPTOR-LIKE PROTEIN KINASE 2 in cyst nematode parasitism of Arabidopsis. Molecular Plant-Microbe Interactions<\/em> 2013;26(1):87-96. https:\/\/doi.org\/10.1094\/MPMI-05-12-0118-FI<\/a><\/li>\n\n\n\n
  54. *Liu S, *Kandoth PK<\/strong>, Warren SD, \u00a3<\/sup>Yeckel G<\/strong>, \u2021<\/sup>Heinz R<\/strong>, \u00b6<\/sup>Alden J<\/strong>, Yang C, Jamai A, El-Mellouki T, Juvale PS, Hill J, Baum TJ, Cianzio S, Whitham SA, Korkin D, \u2020Mitchum MG<\/strong>, and \u2020Meksem K. A soybean cyst nematode resistance gene points to a new mechanism of plant resistance to pathogens. Nature<\/em> 2012;492:256-260. *co-first authors; \u2020co-senior authors https:\/\/doi.org\/10.1038\/nature11651<\/a><\/li>\n\n\n\n
  55. Juvale PS, Hewezi T, Zhang C, Kandoth PK<\/strong>, Mitchum MG<\/strong>, Hill JH, Whitham SA, and Baum TJ. Temporal and spatial Bean pod mottle virus-induced gene silencing in soybean. Molecular Plant Pathology<\/em> 2012;13(9):1140-1148. https:\/\/doi.org\/10.1111\/j.1364-3703.2012.00808.x<\/a><\/li>\n\n\n\n
  56. Hamamouch N, Li C, Hewezi T, Baum TJ, Mitchum MG<\/strong>, Hussey RS, Vodkin LO, and Davis EL. The interaction of the novel 30C02 cyst nematode effector protein with a plant beta-1,3-endoglucanase may suppress host defence to promote parasitism. Journal of Experimental Botany <\/em>2012;63(10):3683-3696. https:\/\/dx.doi.org\/10.1093%2Fjxb%2Fers058<\/a><\/li>\n\n\n\n
  57. *Kandoth PK<\/strong>, *\u00a7<\/sup>Ithal N<\/strong>, Recknor J, Maier T, Nettleton D, Baum TJ, and Mitchum MG<\/strong>. The soybean Rhg1<\/em> locus for resistance to the soybean cyst nematode Heterodera glycines<\/em> regulates expression of a large number of stress- and defense-related genes in degenerating feeding cells. Plant Physiology<\/em> 2011;155:1960-1975. *co-first authors https:\/\/doi.org\/10.1104\/pp.110.167536<\/a><\/li>\n\n\n\n
  58. *Lee C<\/strong>, *\u00a7<\/sup>Chronis D<\/strong>, \u00a7<\/sup>Kenning C<\/strong>, Peret B, Hewezi T, Davis EL, Baum TJ, Hussey RS, Bennett M and Mitchum MG<\/strong>. The novel cyst nematode effector protein 19C07 interacts with the Arabidopsis auxin influx transporter LAX3 to control feeding site development. Plant Physiology <\/em>2011;155:866-880.*co-first authors https:\/\/doi.org\/10.1104\/pp.110.167197<\/a><\/li>\n\n\n\n
  59. \u00a3<\/sup><\/strong>Replogle A<\/strong>, Wang J<\/strong>, Bleckmann A, Hussey RS, Baum TJ, Shinichiro S, Davis EL, Wang X, Simon R, and Mitchum MG<\/strong>. Nematode CLE signaling in Arabidopsis requires CLAVATA2 and CORYNE. The Plant Journal <\/em>2011;65(3):430-440. https:\/\/doi.org\/10.1111\/j.1365-313X.2010.04433.x<\/a><\/li>\n\n\n\n
  60. Wang J<\/strong>, \u00a3<\/sup>Replogle A<\/strong>, Hussey R, Baum T, Wang X, Davis EL, and Mitchum MG<\/strong>. Identification of potential host plant mimics of CLV3\/ESR (CLE)-like peptides from the plant-parasitic nematode Heterodera schachtii<\/em>. Molecular Plant Pathology<\/em> 2011;12(2):177-186. https:\/\/doi.org\/10.1111\/j.1364-3703.2010.00660.x<\/a><\/li>\n\n\n\n
  61. *\u00a3<\/sup>Liu X<\/strong>, *Liu S, Jamai A, Bendahmane A, Lightfoot D, Mitchum MG<\/strong> and Meksem K. Soybean cyst nematode resistance in soybean is independent of the Rhg4<\/em> locus LRR-RLK<\/em> Functional and Integrative Genomics <\/em>2011;11(4):539-549. *co-first authors https:\/\/doi.org\/10.1007\/s10142-011-0225-4<\/a><\/li>\n\n\n\n
  62. *Brown S, *\u00a3<\/sup>Yeckel G<\/strong>, *<\/strong>\u2021<\/sup>Heinz R<\/strong>, Clark K, Sleper D, and Mitchum MG<\/strong>. A high-throughput automated technique for counting females of Heterodera glycines<\/em> using a fluorescence-based imaging system. Journal of Nematology <\/em>2010;42(3):201-206. *co-first authors https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3380484\/<\/a><\/li>\n\n\n\n
  63. Wang J<\/strong>, Joshi S, Korkin D, and Mitchum MG<\/strong>. Variable domain I of nematode CLEs directs post-translational targeting of CLE peptides to the extracellular space. Plant Signaling and Behavior <\/em>2010;5(12):1-3. https:\/\/doi.org\/10.4161\/psb.5.12.13774<\/a><\/li>\n\n\n\n
  64. Wang J<\/strong>, \u00a7<\/sup>Lee C<\/strong>, \u00a3<\/sup>Replogle A<\/strong>, Joshi S, Korkin D, Hussey R, Baum TJ, Davis EL, Wang X and Mitchum MG<\/strong>. Dual roles for the variable domain in protein trafficking and host-specific recognition of Heterodera glycines<\/em> CLE effector proteins. New Phytologist<\/em> 2010;187(4):1003-1017. https:\/\/doi.org\/10.1111\/j.1469-8137.2010.03300.x<\/a><\/li>\n\n\n\n
  65. Patel N, Hamamouch N, Li C, Hewezi T, Hussey RS, Baum TJ, Mitchum MG<\/strong> and Davis EL. A nematode effector protein similar to annexins in host plants. Journal of Experimental Botany <\/em>2010;61(1):235-248. https:\/\/doi.org\/10.1093\/jxb\/erp293<\/a><\/li>\n\n\n\n
  66. Hewezi T, Howe PJ, Maier TR, Hussey RS, Mitchum MG<\/strong>, Davis EL and Baum TJ. Arabidopsis spermidine synthase is targeted by an effector protein of the cyst nematode Heterodera schachtii<\/em>. Plant Physiology <\/em>2010;152(2):968-984. https:\/\/doi.org\/10.1104\/pp.109.150557<\/a><\/li>\n\n\n\n
  67. Sindhu AS, Maier TR, Mitchum MG<\/strong>, Hussey RS, Davis EL and Baum TJ. Effective and specific in planta RNAi in cyst nematodes: Expression interference of four parasitism genes reduces parasitic success. Journal of Experimental Botany<\/em> 2009;60(1):315-324. https:\/\/doi.org\/10.1093\/jxb\/ern289<\/a><\/li>\n\n\n\n
  68. Lu SW, Chen S, Wang J, Yu H, Chronis D, Mitchum MG<\/strong> and Wang X. Structural and functional diversity of CLAVATA3\/ESR (CLE)-like genes from the potato cyst nematode Globodera rostochiensis<\/em>. Molecular Plant-Microbe Interactions <\/em>2009;22(9):1128-1142. https:\/\/doi.org\/10.1094\/MPMI-22-9-1128<\/a><\/li>\n\n\n\n
  69. Patel N, Hamamouch N, Li C, Hussey R, Mitchum MG<\/strong>, Baum T, Wang X and Davis EL. Similarity and functional analyses of expressed parasitism genes in Heterodera schachtii <\/em>and Heterodera glycines<\/em>. Journal of Nematology<\/em> 2008;40(4):299-310.<\/li>\n\n\n\n
  70. *Hu J, *Mitchum MG<\/strong>, Barnaby N, Ayele BT, Ogawa M, Nam E, Lai WC, Hanada A, Alonso JM, Ecker JR, Swain SM, Yamaguchi S, Kamiya Y and Suna TP. Potential sites of bioactive gibberellin production during reproductive growth in Arabidopsis. The Plant Cell <\/em>2008;20(2):320-336.*co-first authors. https:\/\/doi.org\/10.1105\/tpc.107.057752<\/a><\/li>\n\n\n\n
  71. Hewezi T, Howe P, Maier TR, Hussey RS, Mitchum MG<\/strong>, Davis EL and Baum TJ. Cellulose binding protein from the parasitic nematode Heterodera schachtii<\/em> interacts with Arabidopsis pectin methylesterase: Cooperative cell wall modification during parasitism. The Plant Cell <\/em>2008;20(11):3080-3093. https:\/\/doi.org\/10.1105\/tpc.108.063065<\/a><\/li>\n\n\n\n
  72. Wang X, \u00b6<\/sup>Replogle A<\/strong>, Davis EL and Mitchum MG<\/strong>. The tobacco Cel7<\/em> gene promoter is auxin-responsive and locally induced in nematode feeding sites of heterologous plants. Molecular Plant Pathology<\/em> 2007;8(4):423-436. https:\/\/doi.org\/10.1111\/j.1364-3703.2007.00403.x<\/a><\/li>\n\n\n\n
  73. Mitchum MG<\/strong>, Wrather JA, \u2021<\/sup>Heinz RD<\/strong>, Shannon JG and Danekas G. Variability in distribution and virulence phenotypes of Heterodera glycines<\/em> in Missouri during 2005. Plant Disease <\/em>2007;91(11):1473-1476. https:\/\/doi.org\/10.1094\/PDIS-91-11-1473<\/a><\/li>\n\n\n\n
  74. Ithal N<\/strong>, Recknor J, Nettleton D, Maier T, Baum TJ and Mitchum MG<\/strong>. Developmental transcript profiling of cyst nematode feeding cells in soybean roots. Molecular Plant-Microbe Interactions <\/em>2007;20(5):510-525. https:\/\/doi.org\/10.1094\/MPMI-20-5-0510<\/a><\/li>\n\n\n\n
  75. Ithal N<\/strong>, Recknor J, Nettleton D, Hearne L, Maier T, Baum TJ and Mitchum MG<\/strong>. Parallel genome-wide expression profiling of host and pathogen during soybean cyst nematode infection of soybean. Molecular Plant-Microbe Interactions<\/em> 2007;20(3):293-305. https:\/\/doi.org\/10.1094\/MPMI-20-3-0293<\/a><\/li>\n\n\n\n
  76. Wang X, Mitchum MG<\/strong>, Gao B, Li C, Diab H, Baum TJ, Hussey RS and Davis EL. A parasitism gene from a plant-parasitic nematode with function similar to CLAVATA3\/ESR (CLE) of Arabidopsis thaliana<\/em>. Molecular Plant Pathology<\/em> 2005;6(2):187-191. https:\/\/doi.org\/10.1111\/j.1364-3703.2005.00270.x<\/a><\/li>\n\n\n\n
  77. *Mitchum MG<\/strong>, *Yamaguchi S, Hanada A, Kuwahara A, Yoshioka Y, Kato T, Tabata S, Kamiya Y and Sun TP. Distinct and overlapping roles of two gibberellin 3-oxidases in Arabidopsis development. The Plant Journal<\/em> 2006;45(5):804-818. *co-first authors. https:\/\/doi.org\/10.1111\/j.1365-313X.2005.02642.x<\/a><\/li>\n\n\n\n
  78. Mitchum MG<\/strong>, Sukno S, Wang X, Shani Z, Tsabary G, Shoseyov O and Davis EL. The promoter of the Arabidopsis thaliana Cel1<\/em> endo-1,4-beta glucanase gene is differentially expressed in plant feeding cells induced by root-knot and cyst nematodes. Molecular Plant Pathology<\/em> 2004;5(3):175-181. https:\/\/doi.org\/10.1111\/j.1364-3703.2004.00216.x<\/a><\/li>\n\n\n\n
  79. Goellner M<\/strong>, Wang X, and Davis EL. Endo-\u03b2-1,4-glucanase expression in compatible plant-nematode interactions. The Plant Cell<\/em> 2001; 13:2241-2255. https:\/\/doi.org\/10.1105\/tpc.010219<\/a><\/li>\n\n\n\n
  80. Wang X, Allen R, Ding X, Goellner M<\/strong>, Maier T, De Boer J, Baum T, Hussey R, and Davis EL. Signal peptide-selection of cDNA cloned directly from the esophageal gland cells of the soybean cyst nematode Heterodera glycines<\/em>. Molecular Plant-Microbe Interactions<\/em> 2001; 14:536-544. https:\/\/doi.org\/10.1094\/MPMI.2001.14.4.536<\/a><\/li>\n\n\n\n
  81. Goellner M<\/strong>, Smant G, De Boer JM, Baum TJ, and Davis EL. Isolation of \u03b2-1,4-endoglucanase genes from Globodera tabacum<\/em> and their expression during parasitism. Journal of Nematology <\/em>2000; 32(2):154-165. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2620441\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    Members of the Mitchum lab are in bold (with the following designations: \u0166emeritus, \u00a7post-doctoral researcher, \u00a3graduate student, \u2260co-mentored graduate student, \u00b6undergraduate student, \u2021research specialist).<\/p>\n","protected":false},"author":650,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-with-sidebar","meta":{"footnotes":""},"class_list":["post-151","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/site.caes.uga.edu\/mitchumlab\/wp-json\/wp\/v2\/pages\/151","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/site.caes.uga.edu\/mitchumlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/site.caes.uga.edu\/mitchumlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/site.caes.uga.edu\/mitchumlab\/wp-json\/wp\/v2\/users\/650"}],"replies":[{"embeddable":true,"href":"https:\/\/site.caes.uga.edu\/mitchumlab\/wp-json\/wp\/v2\/comments?post=151"}],"version-history":[{"count":10,"href":"https:\/\/site.caes.uga.edu\/mitchumlab\/wp-json\/wp\/v2\/pages\/151\/revisions"}],"predecessor-version":[{"id":1824,"href":"https:\/\/site.caes.uga.edu\/mitchumlab\/wp-json\/wp\/v2\/pages\/151\/revisions\/1824"}],"wp:attachment":[{"href":"https:\/\/site.caes.uga.edu\/mitchumlab\/wp-json\/wp\/v2\/media?parent=151"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}